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Agnes Ayme-Southgate

Professor

Address: HWWE 306
Phone: 843.953.6544
E-mail: southgatea@cofc.edu



Education

University of Geneva, Geneva, Switzerland
   Ph.D. - Biology: Department of Molecular Biology
   B.S. - Biology


Research Interests

  • Genomics and molecular analysis of insect muscle proteins
  • Protein structure-function relationship and biophysical modeling
  • Significance for understanding muscle physiology,  development,  insect flight and evolution

Courses Taught

Biol305: Genetics
Biol312: Molecular Biology and Lab
Biol322: Developmental Biology and Lab
Biol453: Advanced Genetics
FYSM109: Molecular Biology in the News


Publications

Ayme-Southgate A,  Philipp* RA,  and Southgate RJ. (2011) The projectin PEVK domain,  splicing variants and domain structure in basal and derived insects, J. Insect Mol. Biol. 20(3):347-356. PubMed PMID: 21349121.

Ayme-Southgate A,  Southgate RJ,  Philipp* RA,  Sotka AA,  and Kramp* C. (2008) The Myofibrillar Protein,  Projectin,  Is Highly Conserved Across Insect ,   Evolution Except For Its PEVK Domain, J. Mol. Evol. 67(6):653-69.

Ayme-Southgate A, Feldman* S, and Fulmer D*, (2015) Myofilament proteins in the synchronous flight muscles of Manduca sexta show both similarities and differences to Drosophila melanogaster. Insect Biochem.Mol. Biol. 62:174-82

 2Yuan CC, Ma W, Schemmel P, Cheng YS, Liu J, Tsaprailis G, Feldman S*, Ayme Southgate A, and. Irving TC  (2015) Elastic Proteins in the Flight Muscle of Manduca sexta Archives of Biochemistry and Biophysics, 568, 16-27  PMID:25602701

Ayme-Southgate A, R. Allison, E. Berger, L Galloway, E Risner, and J Vance. (2017) Regulation of alternative splicing during the nurse-forager transition in Apis mellifera Arthropod Genomics Conference invited talk